| Courses |
| All courses offered by the uppsala pharmacometrics group are intensive, all-day courses that include both lectures and hands-on exercises. |
| Pharmacokinetic-Pharmacodynamic modeling of Continuous and Categorical data in NONMEM 7 (A NONMEM Workshop for intermediate and advanced users) |
The course presents modeling strategies, techniques and implementations (using NONMEM 7) for the handling of PK-PD information in population models. PD models for continuous data as well as binary, ordered categorical, count and time to event data will be discussed. The course will include explanations and comparisons (with respect to PK-PD modeling) of the different estimation methods available in NONMEM 7. Model diagnostics for PK-PD models including diagnostics for the new estimation methods offered in NONMEM 7 will also be covered. The course will consist of both lectures and hands-on computer exercises using NONMEM 7, PsN and Xpose 4. The participants will be provided with large library of NONMEM code as well as self-instructive material for further studies and exploration of examples for a wide range of PKPD models applied in different disease areas.
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| New features and advanced methods for model building and evaluation in NONMEM VI (A NONMEM Workshop for intermediate and advanced users) |
This course presents some of the most exciting new features of NONMEM VI and how these tools can be used in the development and evaluation of non-linear mixed effects models.
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| Optimal experimental design |
This course gives an introduction to the topic of optimal experimental design. Specifically emphasized will be optimal design of non-linear mixed effects (population) models, which can be especially useful in pre-clinical and clinical drug trials. Both the theoretical and practical aspects of optimal design will be presented, including an introduction to the software PopED developed by the course organizers. The course includes both lectures and hands-on computer exercises done in small groups.
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| Stochastic simulation and estimation |